diff --git a/runtime/vm/thread_interrupter.cc b/runtime/vm/thread_interrupter.cc
index 6f57f4fc205..be990abb53a 100644
--- a/runtime/vm/thread_interrupter.cc
+++ b/runtime/vm/thread_interrupter.cc
@@ -146,6 +146,10 @@ void ThreadInterrupter::WakeUp() {
   }
   {
     MonitorLocker ml(monitor_);
+    if (shutdown_) {
+      // Late call
+      return;
+    }
     if (!initialized_) {
       // Early call.
       return;