diff --git a/pkg/dartdev/lib/src/commands/run.dart b/pkg/dartdev/lib/src/commands/run.dart
index 6992f5dd5b4..93259492aa7 100644
--- a/pkg/dartdev/lib/src/commands/run.dart
+++ b/pkg/dartdev/lib/src/commands/run.dart
@@ -550,6 +550,7 @@ See https://dart.dev/to/package-descriptors for more details.''', verbose) {
       log.stderr(e.message);
       return errorExitCode;
     }
+    DartExecutableWithPackageConfig executableOriginal = executable;
 
     if (useResidentCompiler) {
       final File? residentCompilerInfoFile =
@@ -616,6 +617,9 @@ See https://dart.dev/to/package-descriptors for more details.''', verbose) {
       packageConfigOverride:
           args.option('packages') ?? executable.packageConfig,
       useExecProcess: true,
+      scriptUriOverride: identical(executable, executableOriginal)
+          ? null
+          : executableOriginal.executable,
     );
     return 0;
   }
diff --git a/pkg/dartdev/lib/src/vm_interop_handler.dart b/pkg/dartdev/lib/src/vm_interop_handler.dart
index 20367a0e4e9..a3814aac899 100644
--- a/pkg/dartdev/lib/src/vm_interop_handler.dart
+++ b/pkg/dartdev/lib/src/vm_interop_handler.dart
@@ -34,6 +34,11 @@ abstract class VmInteropHandler {
     // See https://github.com/dart-lang/sdk/issues/53576
     bool markMainIsolateAsSystemIsolate = false,
     bool useExecProcess = false,
+
+    /// When [useExecProcess] pass this path to signal that it originates from
+    /// another file. Used for launching from a dill file while behaving as if
+    /// launched directly from a dart file.
+    String? scriptUriOverride,
   }) {
     List<String> argsList;
     if (useExecProcess && Platform.isWindows) {
@@ -45,6 +50,12 @@ abstract class VmInteropHandler {
         // Escape paths that may contain spaces
         script = '"$script"';
       }
+      if (scriptUriOverride != null &&
+          scriptUriOverride.contains(' ') &&
+          !scriptUriOverride.contains('"')) {
+        // Escape paths that may contain spaces
+        scriptUriOverride = '"$scriptUriOverride"';
+      }
       argsList = [
         for (int i = 0; i < args.length; i++) _windowsArgumentEscape(args[i]),
       ];
@@ -57,6 +68,7 @@ abstract class VmInteropHandler {
     final message = <dynamic>[
       useExecProcess ? _kResultRunExec : _kResultRun,
       script,
+      if (useExecProcess) scriptUriOverride,
       packageConfigOverride,
       markMainIsolateAsSystemIsolate,
       argsList,
diff --git a/pkg/dartdev/test/commands/run_test.dart b/pkg/dartdev/test/commands/run_test.dart
index 800bbb4bd13..7bf617d77f0 100644
--- a/pkg/dartdev/test/commands/run_test.dart
+++ b/pkg/dartdev/test/commands/run_test.dart
@@ -972,6 +972,95 @@ Future<void> main() async {
     expect(result.exitCode, 0);
   });
 
+  test(
+    'resident compiler invocation has working Platform.script',
+    () async {
+      p = project(name: 'foo');
+      p.file('pubspec.yaml', '''
+name: foo
+environment:
+  sdk: '>=2.12.0<3.0.0'
+''');
+      p.file('bin/script1.dart', r'''
+import "dart:io";
+import "dart:isolate";
+
+Future<void> main() async {
+  print("Script1: ${Platform.script}");
+  var exitPort = ReceivePort();
+  var isolate = await Isolate.spawn(
+    entryPoint,
+    "",
+    onExit: exitPort.sendPort,
+  );
+  await exitPort.first;
+
+  exitPort = ReceivePort();
+  await Isolate.spawnUri(
+    Uri.parse("script2.dart"),
+    [],
+    "",
+    onExit: exitPort.sendPort,
+  );
+  await exitPort.first;
+}
+
+void entryPoint(String arg) {
+  print("  -> ${Platform.script}");
+}
+''');
+      p.file('bin/script2.dart', r'''
+import "dart:io";
+import "dart:isolate";
+
+Future<void> main() async {
+  print("Script2: ${Platform.script}");
+  var exitPort = ReceivePort();
+  var isolate = await Isolate.spawn(
+    entryPoint,
+    "",
+    onExit: exitPort.sendPort,
+  );
+  await exitPort.first;
+}
+
+void entryPoint(String arg) {
+  print("  -> ${Platform.script}");
+}
+''');
+
+      var script1 = File(path.join(p.dir.path, 'bin/script1.dart'));
+      expect(script1.existsSync(), true);
+      var script2 = File(path.join(p.dir.path, 'bin/script2.dart'));
+      expect(script2.existsSync(), true);
+
+      ProcessResult pubGetResult = await p.run(['pub', 'get']);
+      expect(pubGetResult.stderr, isEmpty);
+      expect(pubGetResult.exitCode, 0);
+
+      ProcessResult result = await p.run([
+        'run',
+        '--resident',
+        '--$residentCompilerInfoFileOption=$serverInfoFile',
+        'bin/script1.dart',
+      ]);
+
+      String stdout = result.stdout.toString().trim();
+      expect(
+        stdout,
+        '''
+Script1: ${script1.uri}
+  -> ${script1.uri}
+Script2: ${script2.uri}
+  -> ${script2.uri}
+'''
+            .trim(),
+      );
+      expect(result.stderr, isEmpty);
+      expect(result.exitCode, 0);
+    },
+  );
+
   test(
     'passing --resident is a prerequisite for passing --resident-compiler-info-file',
     () async {
diff --git a/runtime/bin/dartdev.cc b/runtime/bin/dartdev.cc
index 7414303cd73..0083656ab43 100644
--- a/runtime/bin/dartdev.cc
+++ b/runtime/bin/dartdev.cc
@@ -606,33 +606,48 @@ class DartDev {
       Syslog::PrintErr("Unable to locate the Dart VM executable");
       Platform::Exit(kErrorExitCode);
     }
+
     ASSERT(GetArrayItem(message, 1)->type == Dart_CObject_kString);
+
+    // scriptUriOverride.
     auto item2 = GetArrayItem(message, 2);
 
     ASSERT(item2->type == Dart_CObject_kString ||
            item2->type == Dart_CObject_kNull);
 
+    // packageConfigOverride.
+    auto item3 = GetArrayItem(message, 3);
+
+    ASSERT(item3->type == Dart_CObject_kString ||
+           item3->type == Dart_CObject_kNull);
+
     package_config_override_ = nullptr;
 
-    if (item2->type == Dart_CObject_kString) {
-      package_config_override_ = Utils::StrDup(item2->value.as_string);
+    if (item3->type == Dart_CObject_kString) {
+      package_config_override_ = Utils::StrDup(item3->value.as_string);
     }
 
-    intptr_t num_vm_options = dart_vm_options_->count();
-    const char** vm_options = dart_vm_options_->arguments();
-    ASSERT(GetArrayItem(message, 4)->type == Dart_CObject_kArray);
-    Dart_CObject* args = GetArrayItem(message, 4);
+    // markMainIsolateAsSystemIsolate
+    auto item4 = GetArrayItem(message, 4);
+    ASSERT(item4->type == Dart_CObject_kBool);
+    const bool mark_main_isolate_as_system_isolate = item4->value.as_bool;
+
+    // argsList
+    ASSERT(GetArrayItem(message, 5)->type == Dart_CObject_kArray);
+    Dart_CObject* args = GetArrayItem(message, 5);
     intptr_t argc = args->value.as_array.length;
     Dart_CObject** dart_args = args->value.as_array.values;
-    auto item3 = GetArrayItem(message, 3);
-    ASSERT(item3->type == Dart_CObject_kBool);
-    const bool mark_main_isolate_as_system_isolate = item3->value.as_bool;
+
     auto deleter = [](char** args) {
       for (intptr_t i = 0; i < argc_; ++i) {
         free(args[i]);
       }
       delete[] args;
     };
+
+    intptr_t num_vm_options = dart_vm_options_->count();
+    const char** vm_options = dart_vm_options_->arguments();
+
     // Total count of arguments to be passed to the script being execed.
     if (mark_main_isolate_as_system_isolate) {
       argc_ = argc + num_vm_options + 5;
@@ -642,6 +657,9 @@ class DartDev {
     if (package_config_override_ != nullptr) {
       argc_++;
     }
+    if (item2->type == Dart_CObject_kString) {
+      argc_++;
+    }
 
     // Array of arguments to be passed to the script being execed.
     argv_ = std::unique_ptr<char*[], void (*)(char**)>(new char*[argc_ + 1],
@@ -697,6 +715,19 @@ class DartDev {
       argv_[idx++] = Utils::SCreate("--packages=%s", package_config_override_);
 #endif
     }
+
+    if (item2->value.as_string != nullptr) {
+#if defined(DART_HOST_OS_WINDOWS)
+      char* script_uri_override =
+          Utils::SCreate("--script_uri_override=%s", item2->value.as_string);
+      argv_[idx++] = StringUtilsWin::ArgumentEscape(script_uri_override);
+      free(script_uri_override);
+#else
+      argv_[idx++] =
+          Utils::SCreate("--script_uri_override=%s", item2->value.as_string);
+#endif
+    }
+
     // Copy in name of the script to run.
     argv_[idx++] = Utils::StrDup(GetArrayItem(message, 1)->value.as_string);
     // Copy in the dart options that need to be passed to the script.
diff --git a/runtime/bin/main_impl.cc b/runtime/bin/main_impl.cc
index 2624ada981d..31d52281e44 100644
--- a/runtime/bin/main_impl.cc
+++ b/runtime/bin/main_impl.cc
@@ -690,9 +690,12 @@ static Dart_Isolate CreateIsolateGroupAndSetupHelper(
   PathSanitizer packages_config_sanitizer(packages_config);
 #endif  // !defined(DART_PRECOMPILED_RUNTIME)
 
-  auto isolate_group_data =
-      new IsolateGroupData(script_uri, asset_resolution_base, packages_config,
-                           app_snapshot, isolate_run_app_snapshot);
+  auto isolate_group_data = new IsolateGroupData(
+      is_main_isolate && Options::script_uri_override() != nullptr
+          ? Options::script_uri_override()
+          : script_uri,
+      asset_resolution_base, packages_config, app_snapshot,
+      isolate_run_app_snapshot);
   if (kernel_buffer != nullptr) {
     isolate_group_data->SetKernelBufferNewlyOwned(kernel_buffer,
                                                   kernel_buffer_size);
diff --git a/runtime/bin/main_options.h b/runtime/bin/main_options.h
index c58c8010608..d6ab3af2026 100644
--- a/runtime/bin/main_options.h
+++ b/runtime/bin/main_options.h
@@ -31,6 +31,7 @@ namespace bin {
   V(executable_name, executable_name)                                          \
   V(resolved_executable_name, resolved_executable_name)                        \
   V(load_module_snapshot, load_module_snapshot)                                \
+  V(script_uri_override, script_uri_override)                                  \
   /* The purpose of these flags is documented in */                            \
   /* pkg/dartdev/lib/src/commands/compilation_server.dart. */                  \
   V(resident_server_info_file, resident_server_info_file_path)                 \